THCP (tetrahydrocannabiphorol) is one of the newest—and most intriguing—cannabinoids to enter the hemp/cannabis space. It’s often marketed as a "super THC" due to its binding strength and psychoactive potential. But what exactly is it? How strong is it? And how safe is it to use? In this guide, you’ll get a clear, up-to-date breakdown of THCP’s science, effects, risks, and how it compares with traditional THC.
Key Takeaways You Should Know
- THCP is a rare cannabinoid with higher receptor affinity than delta‑9 THC.
- It can create stronger effects in smaller doses, meaning potency matters more.
- The research is very limited—much of what we know is from early animal studies.
- Like other THC derivatives, it may show up in drug tests.
- Legal status is ambiguous: currently somewhat tolerated under hemp laws, but could change.
Hands-down: THCP might be one of the most potent cannabinoids, but it's also one of the least understood.
What Is THCP? An Overview
THCP stands for tetrahydrocannabiphorol. It’s a naturally occurring cannabinoid found in trace amounts in cannabis and hemp plants. What sets it apart is its longer alkyl side chain—seven carbon atoms instead of the five commonly found in THC. That extra chain changes how tightly it binds to cannabinoid receptors, potentially amplifying effects.
Because THCP exists in extremely low natural concentrations, most of the THCP products you see—vapes, tinctures, concentrates—are derived via processing, isolation, and formulation, not simply harvested directly from plant bud.
Discovery & Background
THCP was first identified by Italian researchers in 2019 while studying a cannabis cultivar known as FM2. Their research isolated and synthesized THCP and a related cannabinoid, CBDP. They compared its effects to delta‑9 THC in mice—testing parameters like pain response, spontaneous activity, and other behaviors.
That research was groundbreaking: it demonstrated that THCP binds significantly more strongly to CB1 receptors than delta-9 THC, and produces THC-like effects even at tiny concentrations. This underlined the possibility that THCP could be a more powerful alternative to conventional THC.
How THCP Works in the Body
Receptor Binding & Potency
One of THCP’s standout features is that it binds more strongly to the brain’s CB1 receptors than delta‑9 THC. Early research suggests that this binding strength may be 30‑plus times higher in experimental conditions. That means a smaller dose may be needed to achieve effects comparable to THC.
Because THCP can more tightly “lock on” to receptors, it may deliver more intense or longer-lasting effects per milligram.
Mechanisms of Action (Simplified)
- THCP, like other cannabinoids, modulates the endocannabinoid system.
- When it binds to CB1 in the brain and central nervous system, you may get psychoactive or mood-altering effects.
- Binding CB2 (more linked to the immune system) might contribute to anti-inflammatory or therapeutic properties.
- Because of its potency, THCP may magnify both desirable effects and side effects.
Effects, Benefits & Risks
Potential Effects & Benefits
Users and early studies suggest THCP may deliver:
- Stronger psychoactive “high” at lower doses
- Heightened sensory perception
- Deep relaxation, euphoria, or sedation, depending on strain & dose
- Potential pain relief, anti-inflammation, neuroprotection (based on limited animal data)
Because it’s more potent, it can also amplify effects users expect from regular THC—but with greater intensity.
Risks & Side Effects
With potency comes risk. Potential negatives include:
- Anxiety, paranoia, or mental overstimulation
- Dizziness, nausea, confusion
- Dry mouth, red eyes
- Overconsumption is more likely because potency is deceptive
- Unverified product purity or contaminants in low-quality batches
- Unknown long-term health effects (there’s very little human data)
Because THCP is relatively new, more clinical research is needed to understand its full safety profile.
Drug Tests & Detection Risks
Yes—THCP may show up on standard THC drug tests. While testing methods vary, many drug screenings detect common THC metabolites (e.g., THC‑COOH) that could result from consuming THCP or other THC analogs. At this early stage, assume risk: if you’re subject to drug testing (work, legal, etc.), using THCP compounds may jeopardize your results.
Legal Status & Regulations
THCP currently exists in a legal gray zone:
- At the federal level in the U.S., it’s often treated under hemp-derived substance rules, provided THC‑9 levels are under 0.3%.
- But because THCP is psychoactive and more potent, some states may restrict, regulate, or outright ban THCP.
- Also, the DEA or other regulators may decide to schedule it in the future, changing its legal status overnight.
When in doubt: always check your local laws before acquiring THCP products.
How to Use THCP Safely
If you decide to try THCP, here’s a cautious approach:
- Start ultra low: doses of 1–5 mg or less, depending on product potency
- Wait sufficient time before redosing (even 90+ minutes or more)
- Use in comfortable, safe settings—no driving or risky tasks
- Always use third‑party lab-tested, purity-verified products
- Avoid combining with alcohol, sedatives, or stimulants
- Monitor effects and adjust usage accordingly
- Keep detailed notes of dosage, setting, and effects for future reference
Frequently Asked Questions (FAQ)
Q: Is THCP stronger than delta-9 THC?
A: Yes—based on early studies, THCP binds to CB1 receptors more strongly and can elicit effects in smaller doses compared to delta-9.
Q: Does THCP get you psychologically higher?
A: It can. The psychoactivity is often stronger due to binding potency—but individual experience, dose, and tolerance matter a lot.
Q: Can THCP be detected on a drug test?
A: Likely yes. Most standard tests detect THC metabolites that could result from THCP use.
Q: Is THCP legal everywhere?
A: No. It may fall under hemp rules in some places, but many states may restrict or ban it. Always check local laws.
Q: How safe is THCP long-term?
A: We don’t know yet. Because THCP is relatively new, long-term safety data in humans is scarce.
Final Thoughts
THCP is one of the most exciting cannabinoids to emerge in recent years—a compound with the potential to be more potent, more efficient, and more strikingly psychoactive than delta-9 THC. But with novelty comes uncertainty. Its effects may be profound, but so may its risks.
At Burning Daily, we believe in illuminating these frontiers responsibly. Our products come with third-party lab testing, full transparency, and a commitment to education. Try THCP cautiously, always prioritize safety, and stay informed as science progresses.